CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-ACR-0002-0010-10mg | $80 | ||
| VD-ACR-0002-0050-50mg | $300 |
SB 290157 trifluoroacetate salt
$80.00 – $300.00
Product Specification
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Appearance:
Lyophilized.
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CAS Number:
1140525-25-2
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Cat.number:
VD-ACR-0002
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Formula:
C22H28N4O4 · CF3CO2H
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MW:
526.5
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Purity:
≥95%
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Solubility:
DMSO.
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Storage:
-20°C;Protect from Light.
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Synonyms:
N2-[(2,2-Diphenylethoxy)acetyl]-L-arginine, TFA
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Size:
10mg, 50mg
Description
A non-peptide that acts as a selective, high affinity, competitive antagonist of the anaphylatoxin C3a receptor. Does not antagonize C5aR or other chemotactic G-protein-coupled receptors. Blocks C3a-induced internalization of C3aR in human neutrophils and C3a-induced Ca2+ mobilization in basophilic leukemia RBL-2H3 cells expressing murine, guinea pig, or human C3aR. Also blocks C3a-mediated ATP release from Guinea pig platelets. Exhibits anti-inflammatory properties.
1. Ames, R.S., et al. 2001. J. Immunol. 166: 6341-6348.
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