CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-OEIA-10008-0001-1mg | $80 | ||
| VD-OEIA-10008-0005-5mg | $250 |
TrkA Inhibitor
$80.00 – $250.00
Product Specification
-
Appearance:
Yellow solid
-
CAS Number:
388626-12-8
-
Cat.number:
VD-OEIA-10008
-
Formula:
C15H13N3O3S
-
MW:
315.4
-
Purity:
≥97% (sum of two isomers)
-
Solubility:
DMSO
-
Storage:
+2°C to +8°C. Protect from light.
-
Synonyms:
(Z)-4-(((2-oxoindolin-3-ylidene)methyl)amino)benzenesulfonamide
-
Size:
1mg, 5mg
Description
An oxindole compound that acts as a cell-permeable, reversible, potent, and highly selective inhibitor of TrkA (IC50 = 63 nM), presumably by targeting the kinase’s ATP binding pocket. Shown to exhibit ≥150-fold selectivity over Cdk1 and cRaf1.
1.Wood, E.R., et al. 2004. Bioorg. Med. Chem. Lett. 14, 953.
Reviews
There are no reviews yet.