CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-PI-0184-0005-5mg | $150 | ||
| VD-PI-0184-0025-25mg | $500 |
Vialinin A (CAS 858134-23-3)
$150.00 – $500.00
Product Specification
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Appearance:
White Solid
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CAS Number:
858134-23-3
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Cat.number:
VD-PI-0184
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Formula:
C34H26O8
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MW:
562.57
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Purity:
>98%
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Solubility:
20 mM in DMSO
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Storage:
-20°C
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Synonyms:
N/A
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Size:
25mg, 5mg
Description
Vialinin A (CAS 858134-23-3) is an inhibitor of ubiquitin-specific peptidase 4 (USP4), USP5/isopeptidase T (IsoT) and UCH-L1 deubiquitinating enzyme (DUB) activity (IC50 values are 1.5, 5.9 and 22.3 μM, respectively). Shows no significant inhibition of UCH-L3, USP2, and USP8 activities. Decreases release of TNF-α (IC50 = 0.09 nM) from RBL-2H3 mast cells. Displays anti-cancer activity decreasing viability in human colonic carcinoma cells.
1. Norikura et al (2011) J.Agric.Food Chem. 59 6974.
2. Onose et al (2012) Cell Immunol. 279 140.
3. Okada et al (2013) Bioorg.Med.Chem.Lett. 23 4328.
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