CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-IS-0126-0005-5mg | $140 | ||
| VD-IS-0126-0050-50mg | $1150 |
WHI-P154 (CAS 211555-04-3)
$140.00 – $1,150.00
Product Specification
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Appearance:
Pale yellow solid
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CAS Number:
211555-04-3
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Cat.number:
VD-IS-0126
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Formula:
C16H14BrN3O3
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MW:
376.2
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Purity:
>97% by HPLC
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Solubility:
DMSO
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Storage:
RT. Keep cool and dry.
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Synonyms:
JAK3 Inhibitor
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Size:
50mg, 5mg
Description
WHI-P154 (CAS 211555-04-3) is a potent, cell-permeable, and specific inhibitor of JAK3(IC50 = 5.6 μM). Has no effect on either JAK1 or JAK2. Has also been shown to prevent the ionizing radiation-induced activation of c-Jun in DT-40 cells. Also acts as a potent inhibitor of glioblastoma cell adhesion and migration.
1. Narla et al (1998) Clin.Cancer Res. 4 1405.
2. Changelian et al (2008) Blood 111 2155.
3. Sareila et al (2008) Int.Immunopharmacol. 8 100.
4. Kim et al (2010) Stem Cells. 28 1816.
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