Product Variations
Product # | Price | Quantity | |
---|---|---|---|
VD-CRP-0194-0001-1mg | $150 | ||
VD-CRP-0194-0005-5mg | $550 |
$150.00 – $550.00
White Solid
1135688-47-9
VD-CRP-0194
C28H39FN4O10
610.62
>95%
DMSO
-20°C. Protect from moisture.
Z-Ala-Glu(OMe)-Val-Asp(OMe)-FMK, Z-A-E(OMe)-V-Asp(OMe)-FMK
1mg, 5mg
Product # | Price | Quantity | |
---|---|---|---|
VD-CRP-0194-0001-1mg | $150 | ||
VD-CRP-0194-0005-5mg | $550 |
Z-AEVD-FMK (CAS 1135688-47-9) is an irreversible inhibitor of caspase-10 and related caspases.1 At 10 µM, it can prevent the initiation of Fas signaling by caspase-10 in Jurkat T lymphoma cells, preventing Bid cleavage into its active form, caspase cascade activation, and apoptosis.
1. Klinger, S.C., et al. J. Cell Biol. 124, 1095-105, (2011).
2. Wood, J.M., et al. FASEB J. 23, 2065-75, (2009).
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