CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-AIH-0276-0010-10g | $800 | ||
| VD-AIH-0276-0050-50g | $3500 |
3,6-Dibromocarbazole
$800.00 – $3,500.00
Product Specification
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Appearance:
White to brown powder
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CAS Number:
6825-20-3
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Cat.number:
VD-AIH-0276
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Formula:
C12H7Br2N
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MW:
325
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Purity:
97%
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Storage:
Stable. Combustible. Incompatible with strong oxidizing agents.
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Synonyms:
3,6-dibromo-9H-carbazole
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Size:
10g, 50g
Description
A cell-permeable dibromocarbazolo-piperazinyl derivative that displays anti-apoptotic properties. Effectively blocks Bid-induced cyctochrome c release from HeLa cell mitochondria (~80% inhibition at 5 µM) by inhibiting Bax channel-forming activity (IC50 = 520 nM in a liposome channel assay).
Synthesis of 3,6-dibromocarbazole, Yu. N. Polivin, R. A. Karakhanov, V. I. Kelarev, A. A. Bratkov, B. I. Ugrak, G. Kh. Anashkin and M. E. Panina.
Beil. 20,439.
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