ZM 306416 hydrochloride (CAS 690206-97-4)

$40.00$220.00

Product Specification

  • Appearance
    :

    White solid.

  • CAS Number
    :

    690206-97-4

  • Cat.number
    :

    VD-AM-0106

  • Formula
    :

    C16H13N3O2FCl.HCl

  • MW
    :

    370.21

  • Purity
    :

    >98% (HPLC)

  • Solubility
    :

    10 mM in DMSO.

  • Storage
    :

    RT

  • Synonyms
    :

    N‐(4‐chloro‐2‐fluorophenyl)‐6,7‐dimethoxyquinazolin‐4‐aminehydrochloride

  • Size
    :

    10mg, 1mg

SKU: VD-AM-0106 Categories: ,

Product Variations

Product # Price Quantity  
VD-AM-0106-0001-1mg $40
VD-AM-0106-0010-10mg $220

Description

ZM 306416 hydrochloride (CAS 690206-97-4) is an inhibitor of vascular endothelial growth factor (VEGF) receptor tyrosine kinase. Inhibits activity of KDR and FLT VEGF receptors (IC50 values are 100 nM and 2 μM respectively) and displays > 3-fold selectivity over FGFR-1. Orally active in vivo.

1. Hennequin et al (1999) J.Med.Chem. 42 5369.

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