Ac-YVAD-CHO (CAS 174063-88-8)

$50.00$180.00

Product Specification

  • Appearance
    :

    White powder.

  • CAS Number
    :

    174063-88-8

  • Cat.number
    :

    VD-CRP-0196

  • Formula
    :

    C23H32N4O8

  • MW
    :

    492.5

  • Purity
    :

    >=98% by (HPLC)

  • Solubility
    :

    DMSO

  • Storage
    :

    -20°C.Protect from moisture.

  • Synonyms
    :

    Caspase-1 Inhibitor I; Ac-Tyr-Val-Ala-Asp-CHO

  • Size
    :

    1mg, 5mg

SKU: VD-CRP-0196 Categories: ,

Product Variations

Product # Price Quantity  
VD-CRP-0196-0001-1mg $50
VD-CRP-0196-0005-5mg $180

Description

Ac-YVAD-CHO (CAS 174063-88-8) is a potent, specific, and reversible inhibitor of caspase-1 (Ki = 200 pM for human recombinant caspase-1), caspase-4, and caspase-5. Strongly inhibits anti-APO-1 induced apoptosis in L929-APO-1 cells.

1.Garcia-Calvo, M., et al. 1998. J. Biol. Chem. 273, 32608.
2.Hilbi, H., et al. 1998. J. Biol. Chem. 273, 32895.
3.Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
4.Los, M., et al. 1995. Nature 375, 81.

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