CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-AI-0083-0010-10mg | $50 | ||
| VD-AI-0083-0050-50mg | $200 |
CI 994 (CAS 112522-64-2)
$50.00 – $200.00
Product Specification
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Appearance:
Off-white solid
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CAS Number:
112522-64-2
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Cat.number:
VD-AI-0083
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Formula:
C15H15N3O2
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MW:
269.3
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Purity:
>=99%
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Solubility:
DMSO
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Storage:
+4°C.
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Synonyms:
N-acetyldinaline, 4-(Acetylamino)-N-(2-aminophenyl)benzamide
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Size:
10mg, 50mg
Description
CI 994 (CAS 112522-64-2) is an orally active histone deacetylase (HDAC) inhibitor (Ki values are 0.41, 0.75, >100 and >100 μM for HDAC1, HDAC3, HDAC6 and HDAC8 respectively). Mediates G1 cell cycle arrest, inhibits proliferation and induces apoptosis in vitro and in vivo.
1. Kraker et al (2003) Mol.Cancer Ther. 2 401.
2. Loprevite et al (2005) Oncol.Res. 15 39.
3. Beckers et al (2007) Int.J.Cancer 121 1138.
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