CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-IS-0045-0010-10mg | $70 | ||
| VD-IS-0045-0050-50mg | $300 |
AG 213 (CAS 122520-86-9)
$70.00 – $300.00
Product Specification
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Appearance:
Yellow/orange solid
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CAS Number:
122520-86-9
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Cat.number:
VD-IS-0045
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Formula:
C10H8N2O2S
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MW:
220.25
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Purity:
≥97%
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Solubility:
25 mM in EtOH, 100 mM in DMSO
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Storage:
+4°C.
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Synonyms:
TyrphostinAG 213
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Size:
10mg, 50mg
Description
AG 213 (CAS 122520-86-9) is an epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor (PDGFR) kinase inhibitor (IC50 values are 2.4 and 3 μM respectively). Stimulates microtubule polymerization and promotes neurite outgrowth > 17-fold over basal conditions in vitro. Also weakly inhibits protein kinase C (IC50 = 60 μM).
1. Yaish et al 1988) Science 242 933.
2. Gazit et al (1989) J.Med.Chem. 32 2344.
3. Levitzki and Gazit (1995) Science 267 1782.
4. Plouffe et al (2006) Endocrinology 147 4646.
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