AICAR (CAS 2627-69-2)

$50.00$150.00

Product Specification

  • Appearance
    :

    White Solid

  • CAS Number
    :

    2627-69-2

  • Cat.number
    :

    VD-ESA-0015

  • Formula
    :

    C9H14N4O5

  • MW
    :

    258.23

  • Purity
    :

    >99%

  • Solubility
    :

    75 mM in water and to 75 mM in DMSO

  • Storage
    :

    -20°C

  • Synonyms
    :

    Aicar, Acadesine, Aica-riboside, NSC-105823, NSC105823, N1-(β-D-Ribofuranosyl)-5-aminoimidazole-4-carboxamide

  • Size
    :

    200mg, 50mg

SKU: VD-ESA-0015 Category:

Product Variations

Product # Price Quantity  
VD-ESA-0015-0050-50mg $50
VD-ESA-0015-0200-200mg $150

Description

AICAR (CAS 2627-69-2)  a cell-permeable, allosteric activator of AMP-activated protein kinase (AMPK). Augments proliferation, differentiation and mineralization of osteoblastic MC3T3-EI cells and attenuates psychosine-induced expression of proinflammatory cytokines and iNOS in astrocytes. Promotes osteogenic differentiation of hAMSCs and BM-MSCs in vitro

1. Giri et al (2004)  J.Neurosci. 24 479.
2. Kanazawa et al (2007) BMC Cell Biol. 8 51.
3. Giri et al (2008) J.Neurochem. 105 1820.
4. Wu et al (2011) Int.J.Artif.Organs. 34 1128.

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