Product Variations
Product # | Price | Quantity | |
---|---|---|---|
VD-CCR-0036-0010-10mg | $100 | ||
VD-CCR-0036-0100-100mg | $850 |
$100.00 – $850.00
Red solid.
118458-54-1
VD-CCR-0036
C20H11N3O2 . C2H5OH . 1/4 H2O
371.39
≥95%
100 mM in DMSO
-20°C. Protect from light.
12,13-Dihydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazole-5 ,7(6H)-dione
100mg, 10mg
Product # | Price | Quantity | |
---|---|---|---|
VD-CCR-0036-0010-10mg | $100 | ||
VD-CCR-0036-0100-100mg | $850 |
Arcyriaflavin A (CAS 118458-54-1) is a potent inhibitor of cdk4/cyclin D1 (IC50=59 nM). Also active against CaM kinase II (IC50=25 nM) but displays selectivity over several other kinases in vitro (IC50 values for inhibition of PKA and PKC are >2 and >100 μM respectively). Inhibits human cytomegalovirus (HCMV) replication in vitro (IC50=200 nM).
1.Slater et al (1999) Bioorg.Med.Chem. 7 1067.
2.Zhu et al (2003) Bioorg.Med.Chem.Lett. 13 1231.
3.Sanchez-Martinez et al (2003) Bioorg.Med.Chem.Lett. 13 3835.
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