CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-ACR-0005-0010-10mg | $100 | ||
| VD-ACR-0005-0050-50 mg | $400 |
D-24851
$100.00 – $400.00
Product Specification
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Appearance:
Off-white solid.
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CAS Number:
204205-90-3
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Cat.number:
VD-ACR-0005
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Formula:
C22H16ClN3O2
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MW:
389.8
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Purity:
≥98%
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Solubility:
DMSO
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Storage:
-20°C. Protect from light.
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Synonyms:
N-(Pyridin-4-yl)-[1-(4-chlorobenzyl)-indol-3-yl]-glyoxyl Amide
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Size:
10mg, 50mg
Description
A cell-permeable, potent anticancer agent that destabilizes microtubules in tumor cells as well as in a cell-free system. Binds directly to tubulin and inhibits polymerization (IC50 = 300 nM). Also blocks cell cycle at G2/M phase, shows efficacy toward multidrug-resistant (MDR) tumor cells, and shows no neurotoxicity.
1.Bacher, G., et al. 2001. Cancer Res. 61, 392.
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