CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-ACR-0009-0010-10mg | $50 | ||
| VD-ACR-0009-0025-25mg | $80 |
FAK Inhibitor 14 (CAS 4506-66-5)
$50.00 – $80.00
Product Specification
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Appearance:
Grey to brown solid.
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CAS Number:
4506-66-5
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Cat.number:
VD-ACR-0009
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Formula:
C6H10N4 . 4HCl
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MW:
284.01
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Purity:
>=90%
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Solubility:
Water or DMSO.
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Storage:
RT. Keep cool and dry.
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Synonyms:
1,2,4,5-Benzenetetramine tetrahydrochloride
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Size:
10mg, 25mg
Description
FAK Inhibitor 14 (CAS 4506-66-5) is a selective focal adhesion kinase (FAK) inhibitor that displays no significant activity at a range of other kinases including EGFR, PDGFR and IGF-RI. Prevents FAK autophosphorylation at Y397 (IC50 = 1 μM), promotes cell detachment and inhibits cell adhesion in vitro. Exhibits antiproliferative activity in a variety of human tumor cell lines in vitro and in breast cancer cells in vivo.
1. Golubovskaya et al (2008), J.Med.Chem. 51 7405.
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