CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-AM-0056-0010-10mg | $140 | ||
| VD-AM-0056-0050-50mg | $500 |
SU 4312 (CAS 5812-07-7)
$140.00 – $500.00
Product Specification
-
Appearance:
Orange-red solid
-
CAS Number:
5812-07-7
-
Cat.number:
VD-AM-0056
-
Formula:
C17H16N2O
-
MW:
264.32
-
Purity:
≥98% (HPLC)
-
Solubility:
Soluble to 30 mg/mL in DMSO
-
Storage:
-20°C. Air and light sensitive.
-
Synonyms:
DMBI; 3-[[4-(dimethylamino)phenyl] methylene]-1,3-dihydro-2H-indol-2-one
-
Size:
10mg, 50mg
Description
SU 4312 (CAS 5812-07-7) is a cell-permeable, reversible, ATP-competitive, and potent inhibitor of the tyrosine kinase activities of the PDGF β-receptor (β-PDGFR; IC50 = 4 µM in PAC-1 cells) and FGFR1 (IC50 = 5 µM for inhibition of tyrosine phosphorylation of p90). Does not inhibit EGFR or c-Src tyrosine kinases, even at concentrations greater than 100 µM.
1. Zaman et al (1998) Biochem.Pharmacol. 57 57.
2. Sun et al (1998) J.Med.Chem. 41 2588.
3. Kendall et al (1999) J.Biol.Chem. 274 6453.
Reviews
There are no reviews yet.