CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-CCR-0118-0010-10mg | $110 | ||
| VD-CCR-0118-0050-50mg | $450 |
iCRT 14 (CAS 677331-12-3)
$110.00 – $450.00
Product Specification
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Appearance:
Yellow to orange
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CAS Number:
677331-12-3
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Cat.number:
VD-CCR-0118
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Formula:
C21H17N3O2S
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MW:
375.44
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Purity:
>=99%.
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Solubility:
DMSO (75 mM).
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Storage:
+2°C to +8°C. Protect from light.
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Synonyms:
Not available.
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Size:
10mg, 50mg
Description
iCRT 14 (CAS 677331-12-3) is a potent inhibitor of β-catenin-responsive transcription (CRT) (IC50 = 40.3 nM in assays of Wnt pathway activity). Thought to directly influence the interaction between β-catenin and TCF4. Induces marked G0/G1 cell cycle arrest in HCT-116 and HT29 cell lines.
1. Watanabe and Dai (2011) Proc.Natl.Acad.Sci.USA 108 5929.
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