CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-IS-0084-0001-1mg | $60 | ||
| VD-IS-0084-0010-10mg | $580 |
M 344 (CAS 251456-60-7)
$60.00 – $580.00
Product Specification
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Appearance:
White Solid
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CAS Number:
251456-60-7
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Cat.number:
VD-IS-0084
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Formula:
C16H25N3O3
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MW:
307.39
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Purity:
≥98% by HPLC
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Solubility:
100 mM in DMSO and to 20 mM in Ethanol
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Storage:
-20°C. Protect from light.
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Synonyms:
M 344
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Size:
10mg, 1mg
Description
M 344 (CAS 251456-60-7) is a histone deacetylase inhibitor (IC50 = 100 nM). Induces terminal cell differentiation and causes an increase in hyperacetylated histone H4. Antiproliferative agent; suppresses the growth of human endometrial and ovarian cancer cells by inducing cell cycle arrest and apoptosis.
1. Jung et al (1999) J.Med.Chem. 42 4669.
2. Takai et al (2006) Gynecol.Oncol. 101 108.
3. Riessland et al (2006) Hum.Genet. 120 101.
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