Product Variations
Product # | Price | Quantity | |
---|---|---|---|
VD-AI-0281-0005-5mg | $120 | ||
VD-AI-0281-0050-50mg | $1000 |
$120.00 – $1,000.00
Yellow orange solid
861891-50-1
VD-AI-0281
C19H23N3O2
325.4
≥95%
DMSO or Methanol.
+4°C.
1-methyl-3-(1-methyl-1H-indol-3-yl)-4-(pentylamino)-1H-pyrrole-2,5-dione
50mg, 5mg
Product # | Price | Quantity | |
---|---|---|---|
VD-AI-0281-0005-5mg | $120 | ||
VD-AI-0281-0050-50mg | $1000 |
A cell-permeable mono-indolylmaleimide compound that selectively blocks oxidative stress-induced necrotic cell death (~3 µM IM-54 prevented ~50% cell death in HL60 cells exposed to 100 µM H2O2). Does not offer protection against Etoposide induced apoptosis or display antioxidant properties. Does not affect the kinase activities of S6K1 and PKC isozymes even at concentrations as high as 50 µM.
1. Dodo, K., et al. 2005. Bioorg. Med. Chem. Lett. 15: 3114-3118.
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