PT 1 (CAS 331002-70-1)

$120.00$500.00

Product Specification

  • Appearance
    :

    Brown solid

  • CAS Number
    :

    331002-70-1

  • Cat.number
    :

    VD-ESA-0027

  • Formula
    :

    C23H16ClN3O6S

  • MW
    :

    497.91

  • Purity
    :

    >98%

  • Solubility
    :

    100 mM in DMSO and to 100 mM in 1.1eq. NaOH.

  • Storage
    :

    -20°C

  • Synonyms
    :

    PT 1

  • Size
    :

    10mg, 50mg

SKU: VD-ESA-0027 Category:

Product Variations

Product # Price Quantity  
VD-ESA-0027-0010-10mg $120
VD-ESA-0027-0050-50mg $500

Description

PT 1 (CAS 331002-70-1) is an AMP-activated protein kinase (AMPK) activator. Stimulates AMPK heterotrimer (α1β1γ1) activity (EC50 = 0.3 μM). Thought to directly activate AMPK by antagonizing autoinhibition.

1. Pang et al (2007)  J.Biol.Chem. 283 16051.
2. Zorn and Wells (2010) Nat.Chem.Biol. 6 179.

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