CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-AIH-0292-0025-25mg | $200 | ||
| VD-AIH-0292-0100-100mg | $600 |
QNZ (CAS 545380-34-5)
$200.00 – $600.00
Product Specification
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Appearance:
Crystalline solid.
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CAS Number:
545380-34-5
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Cat.number:
VD-AIH-0292
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Formula:
C22H20N4O
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MW:
356.4
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Purity:
>=98%.
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Solubility:
DMSO (20 mg/ml), DMF (30 mg/ml).
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Storage:
-20°C. Protect from light.
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Synonyms:
N4-[2-(4-phenoxyphenyl)ethyl]-4,6-quinazolinediamine
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Size:
100mg, 25mg
Description
QNZ inhibits the activation of the transcription factor NF-κB and has been used to investigate NF-κB signaling. Improper activation of NF-κB has been linked to cancer, immune and inflammatory diseases, and viral infection. Research results suggest that QNZ fully blocks the increase in K currents in rat sensory neurons. QNZ has been used to study colorectal cancer and Schwann cell functioning.
1.Tobe, M., et al. 2003. Bioorg. Med. Chem. 11: 3869-3878.
2.Choi, S., et al. 2006. J. Biol. Chem. 281: 12722-12728.
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