RETRA hydrochloride (CAS 1173023-52-3)

$110.00$400.00

Product Specification

  • Appearance
    :

    Off-white solid

  • CAS Number
    :

    1173023-52-3

  • Cat.number
    :

    VD-CCR-0126

  • Formula
    :

    C11N11NO3S2.HCl

  • MW
    :

    305.8

  • Purity
    :

    >99%

  • Solubility
    :

    100 mM in DMSO

  • Storage
    :

    RT

  • Size
    :

    10mg, 50mg

SKU: VD-CCR-0126 Categories: ,

Product Variations

Product # Price Quantity  
VD-CCR-0126-0010-10mg $110
VD-CCR-0126-0050-50mg $400

Description

RETRA hydrochloride (CAS 1173023-52-3) is an antitumor agent. Inhibits tumor cell growth in a mutant p53- and p73-dependent manner in vitro and in vivo (IC50 = 4 μM). Transcriptionally activates expression of p53-responsive genes and induces activation of effector caspases 3 and 7.

1. Kravchenko et al (2008) Proc.Natl.Acad.Sci.USA 105 6302.

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