Rho/SRF Pathway Inhibitor, CCG-1423

$20.00$85.00

Product Specification

  • Appearance
    :

    White solid.

  • CAS Number
    :

    285986-88-1

  • Cat.number
    :

    VD-GFC-0126

  • Formula
    :

    C18H13ClF6N2O3

  • MW
    :

    454.8

  • Purity
    :

    >=97% by HPLC

  • Solubility
    :

    DMSO (10mg/ml).

  • Storage
    :

    Store at +2 – 8°C.

  • Synonyms
    :

    CCG-1423

  • Size
    :

    25mg, 5mg

SKU: N/A Categories: ,

Product Variations

Product # Price Quantity  
VD-GFC-0126-0005-5mg $20
VD-GFC-0126-0025-25mg $85

Description

A cell-permeable benzamide compound that acts as an effective inhibitor against RhoA- and RhoC-mediated cellular activities by targeting signaling events downstream of Gα12/13 and RhoA/C, affecting MKL recruitment and/or postrecruitment function of MKL1, but not SRF-SRE interaction or ROCK kinase activity.

1.C.R. Evelyn, et al.; Mol. Cancer Ther. 6, 2249 (2007).

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