CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-IS-0069-0010-10mg | $70 | ||
| VD-IS-0069-0050-50mg | $325 |
SD 169 (CAS 1670-87-7)
$70.00 – $325.00
Product Specification
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Appearance:
Off-white solid
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CAS Number:
1670-87-7
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Cat.number:
VD-IS-0069
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Formula:
C9H8N2O
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MW:
160.17
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Purity:
>=97%
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Solubility:
10 mM in H2O and to 100 mM in DMSO.
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Storage:
+2°C to +8°C. Protect from light.
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Synonyms:
p38 MAP Kinase Inhibitor VII
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Size:
10mg, 50mg
Description
SD 169 (CAS 1670-87-7) is a selective, orally active, ATP-competitive inhibitor of p38α MAPK (IC50 values are 3.2, 122 and > 50000 nM for p38α, p38β and p38γ respectively). Demonstrates no activity against a range of other kinases including ERK2, JNK1 and MAPKAP2. Prevents development of diabetes and alleviates mild and moderate hyperglycaemic states in NOD mice.
1.Myers et al (2003).Exp.Neurol. 184 606.
2.Medicherla et al (2006).Exp.Ther. 318 99.
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