CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-IS-0086-0100-100mg | $40 | ||
| VD-IS-0086-0500-500mg | $150 |
Sodium 4-Phenylbutyrate (CAS 1716-12-7)
$40.00 – $150.00
Product Specification
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Appearance:
White Solid
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CAS Number:
1716-12-7
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Cat.number:
VD-IS-0086
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Formula:
C10H11NaO2
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MW:
186.18
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Purity:
>99%
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Solubility:
100 mM in Water or DMSO
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Storage:
-20°C
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Synonyms:
4-PB, Sodium phenylbutyrate, 4-Phenylbutyric acid, sodium salt
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Size:
100mg, 500mg
Description
Sodium 4-Phenylbutyrate (CAS 1716-12-7) is a histone deacetylase inhibitor that displays anticancer activity. Inhibits cell proliferation, invasion and migration and induces apoptosis in glioma cells. Also inhibits protein isoprenylation, depletes plasma glutamine, increases production of fetal hemoglobin through transcriptional activation of the γ-globin gene and affects hPPARγ activation.
1. Engelhard et al (1998) J.Neuro-Oncol. 37 97.
2. Appelskog et al (2004) Int.J.Oncol. 24 1419.
3. Ammerpohl et al (2007) Br.J.Cancer 96 73.
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