CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-IS-0046-0010-10mg | $70 | ||
| VD-IS-0046-0050-50mg | $300 |
AG 494 (CAS 133550-35-3)
$70.00 – $300.00
Product Specification
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Appearance:
Yellow solid.
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CAS Number:
133550-35-3
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Cat.number:
VD-IS-0046
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Formula:
C16H12N2O3
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MW:
280.28
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Purity:
>=98%.
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Solubility:
5 mM in EtOH, 50 mM in DMSO.
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Storage:
+4°C.
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Synonyms:
(E)-2-Cyano-3-(3,4-di-hydroxy phenyl)-N-phenyl-2-propenamide
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Size:
10mg, 50mg
Description
AG 494 (CAS 133550-35-3) is a potent inhibitor of epidermal growth factor receptor (EGFR) kinase (IC50=0.7 μM). Selective over ErbB2, PDGFR and insulin receptor kinase (IC50 values are 42, 6 and >100 μM respectively).
1.Ben-Bassat et al (1999) J.Pharmacol.Exp.Ther. 290 1442.
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