LY 294002 (CAS 154447-36-6)

$80.00$300.00

Product Specification

  • Appearance
    :

    White crystalline solid.

  • CAS Number
    :

    154447-36-6

  • Cat.number
    :

    VD-CCR-0117

  • Formula
    :

    C19H17NO3.HCl

  • MW
    :

    343.81

  • Purity
    :

    >=98%

  • Solubility
    :

    DMSO to 25 mM.

  • Storage
    :

    RT. Keep cool and dry.

  • Synonyms
    :

    2-morpholino-8-phenyl-4H-chromen-4-one hydrochloride

  • Size
    :

    25mg, 5mg

SKU: VD-CCR-0117 Categories: ,

Product Variations

Product # Price Quantity  
VD-CCR-0117-0005-5mg $80
VD-CCR-0117-0025-25mg $300

Description

LY 294002 (CAS 154447-36-6) is a highly selective inhibitor of phosphatidylinositol 3-kinase (IC50 values are 0.31, 0.73, 1.06 and 6.60 μM for PI3Kβ, PI3Kα, PI3Kδ and PI3Kγ respectively). Inhibits proliferation and induces apoptosis in human colon cancer cells in vitro and in vivo.

1.Vlahos et al (1994. J.Biol.Chem. 269 5241.
2.Chasserot-Golaz et al (1998). J.Neurochem. 70 2347.

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