CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-CCR-0120-0010-10mg | $100 | ||
| VD-CCR-0120-0050-50mg | $400 |
NSC 319726 (CAS 71555-25-4)
$100.00 – $400.00
Product Specification
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Appearance:
White solid.
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CAS Number:
71555-25-4
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Cat.number:
VD-CCR-0120
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Formula:
C11H14N4S
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MW:
234.32
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Purity:
>98%
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Solubility:
100 mM in DMSO and to 10 mM in ethanol with gentle warming.
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Storage:
-20°C
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Synonyms:
NSC319726
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Size:
10mg, 50mg
Description
NSC 319726 (CAS 71555-25-4) is a reactivator of mutant p53. Restores wild type p53 structure and function to the p53R175 mutant. Inhibits growth of fibroblasts expressing the p53R175 mutation (IC50 = 8 nM). Also inhibits growth of xenograft tumors expressing the p53R175 mutation in vivo.
1. Yu et al (2012) Cancer Cell 21 614.
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