Product Variations
Product # | Price | Quantity | |
---|---|---|---|
VD-GFC-0121-0001-1mg | $80 | ||
VD-GFC-0121-0005-5mg | $425 |
$80.00 – $425.00
Yellow solid
15966-93-5
VD-GFC-0121
C18H18N2O3
310.4
≥95% by HPLC
DMSO, EtOH.
-20°C. Protect from light. Packaged under inert gas.
VEGF Receptor 2 Kinase Inhibitor I; (Z)-3-[(2,4-Dimethyl-3-(ethoxycarbonyl)pyrrol- 5-yl)methylidenyl]indolin-2-one
1mg, 5mg
Product # | Price | Quantity | |
---|---|---|---|
VD-GFC-0121-0001-1mg | $80 | ||
VD-GFC-0121-0005-5mg | $425 |
A highly selective, cell-permeable indolin-2-one class of receptor tyrosine kinase (RTK) inhibitor (IC50 = 70 nM) for murine vascular endothelial growth factor receptor 2 (VEGF-R2; KDR/Flk-1). The inhibition is suggested to be competitive with respect to ATP. Does not inhibit PDGF, EGF, and IGF-1 RTK activities (IC50 > 100 M).
Sun, L., et al. 1998. J. Med. Chem. 41, 2588.
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