CARTProduct Variations
| Product # | Price | Quantity | |
|---|---|---|---|
| VD-IS-0070-0010-10mg | $100 | ||
| VD-IS-0070-0050-50mg | $450 |
XRP44X (CAS 729605-21-4)
$100.00 – $450.00
Product Specification
-
Appearance:
White Solid
-
CAS Number:
729605-21-4
-
Cat.number:
VD-IS-0070
-
Formula:
C21H21ClN4O
-
MW:
380.87
-
Purity:
>99%
-
Solubility:
100 mM in DMSO and to 50 mM in Ethanol.
-
Storage:
RT
-
Synonyms:
1-(3-Chlorophenyl)-4-[(3-methyl-1-phenyl- 1H-pyrazol-5-y l)carbonyl]piperazine
-
Size:
10mg, 50mg
Description
XRP44X (CAS 729605-21-4) is a Ras-Net (Elk-3) pathway inhibitor (IC50 = 10-20 nM). Indirectly inhibits Net phosphorylation upstream of Erk1/2 activation. Mediates G2-M cell cycle arrest, suppresses growth of multiple cell types (IC50 ~ 2 nM), inhibits angiogenesis and acts as a microtubule depolymerizing agent in vitro.
1. Wasylyk et al (2008) Cancer Res. 68 1275.
Reviews
There are no reviews yet.